Jonathan Thielman

Graduate Student (2nd Year) Colorado State University

B.S. Duke University, 2013

Hometown: Birmingham, AL

Research










The baulamycins are a series of structurally-novel antibiotics isolated from Streptomyces tempisquensis in early 2014. Found to inhibit siderophore biosynthesis, these partially-deoxygenated polyketides are active in the low micromolar range against both Gram-positive and Gram-negative bacteria. The development of a concise, enantioselective route towards Baulamycin A and B suggests the compelling possibility of further investigation into the bioactivity of these unique natural products.

"A man's worth is no greater than his ambitions." - Aurelius

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